Pharmacokinetics of Cefadroxil and Cefaclor During an Eight-Day Dosage Period
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چکیده
منابع مشابه
Comparative pharmacokinetics of cephalexin, cefaclor, cefadroxil, and CGP 9000.
In a randomized crossover study, the pharmacokinetics of three new cephalosporin antibiotics, cefaclor, cefadroxil, and CGP 9000, in comparison to cephalexin, were determined after oral administration, by capsules, of 1,000 mg on an empty stomach in 12 normal subjects. Serum concentrations were measured during a period of 8 h, and urine recovery was measured during 24 h. The significant paramet...
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The pharmacokinetics of cefaclor and cephalexin were characterized in patients with creatinine clearances ranging from 0 to 147 ml/min. Each of 24 fasted subjects received a single 500-mg oral dose of cefaclor, and 13 of these subjects later received 500 mg of cephalexin. Serum and urine levels of the antibiotics were measured by bioassay. The serum half-lives were highly correlated with correc...
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Colorimetric Determination of Cefadroxil and Ceftriazone in Pharmaceutical Dosage Forms
Purpose: To develop a simple, rapid and selective method for the spectrophotometric determination of cefadroxil and ceftriaxone using 1, 2napthaquinone-4sulfonic acid sodium. Methods: The method was based on the derivatization of cefadroxil and ceftriaxone with 1, 2naphthaquinone-4sulfonic acid sodium in alkaline medium to yield orange-colored products. Results: The reaction products of cefadro...
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conclusions it was concluded that snake bite cases in kashan are similar to other areas in iran from an epidemiological point of view, including; age distribution rates, gender and site of the bites. the existence of macrov ipera lebetina, a dangerous venomous snake, can cause a range of clinical effects among residents in central parts of iran, such as kashan area. patients and methods this re...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1982
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.22.6.1061